Pharmacological potential of Cytisus triflorus l ’ Hérit . extracts as antioxidant and anti - inflammatory agent

This work aimed to investigate the anti-inflammatory and the antioxidant activities of the hydroalcolic extract (HAEs) from aerial parts (stems and leaves separately) of an Algerianmedicinal plantCytisustriflorusL’Hérit. The anti-inflammatory activity is evaluated by the carrageenan induced mice hind paw edema model. Oral administration of HAEs tested at the dose of 200 and 400 mg/kg body weight produced significant decrease of the paw edema, in a dose dependant manner. HAEs of leaves and stems showed the maximum inhibitory effect (60,5% and 28,73 %, respectively) at the 4 hours for the 400 mg/kg dose. The plant extracts exhibited DPPH radical scavenging potential with IC50 values of 19,17μg/mland77,81μg/mlfor leaf and stem hydroalcolic extracts, respectively. The total amount of phenolic compounds and flavonoids accounted for 240 mg/g and 52.13 mg/g of the HAE from leaves and 166,5 mg/g and 16.82 mg/g of the HAE from stems, respectively, which were evaluated using the Follin-Ciocalteau and aluminium chloride methods, respectively. The results suggest that the HAEs from leaves of Cytisustriflorus may be considered as a good source of phytopharmaceutical anti-inflammatories.